A Setback for MDMA-Assisted Psychotherapy
An FDA advisory committee concluded that MDMA's benefits had not been shown to outweigh its risks.
An FDA advisory committee concluded that MDMA's benefits had not been shown to outweigh its risks.
Plus: A listener asks the editors about tariffs and subsidies in the manufacture of electric vehicles.
The FDA, which approved the protocols for the studies it now questions, is asking for an additional Phase 3 clinical trial, which would take years and millions of dollars.
The panel's recommendation, based on several concerns about two clinical trials, is a serious setback for a promising PTSD treatment.
Historian Erika Dyck contextualizes the deep roots of and battles over LSD, psilocybin, and other psychoactive substances.
The former Texas governor on helping veterans with PTSD, increasing legal immigration, and the illegal drug he'd most like to try
Historian Erika Dyck wants to document the deep roots of and battles over LSD, psilocybin, and other psychoactive substances.
The founder of MAPS talks about FDA approval for MDMA-assisted therapy and the "psychedelic renaissance" he has helped create.
Reason's Nick Gillespie talked with Mauss, a comedian who tours the country discussing his psychedelic experiences, at the Psychedelic Science 2023 conference.
The former Texas governor on helping veterans with PTSD, increasing legal immigration, and the illegal drug he'd most like to try
Reason's Nick Gillespie talked with MAPS founder Rick Doblin about the imminent FDA approval of MDMA- and psilocybin-assisted therapy at the Psychedelic Science conference in Denver.
A documentary short about a woman who takes ayahuasca to alleviate the pain caused by addiction
The bill is the latest sign of strange new respect for drugs that were once routinely depicted as menaces to body and soul.
Subjects diagnosed with severe post-traumatic stress disorder made substantially more progress when they received MDMA rather than a placebo.
Neuropsychopharmacologist Carl Hart says most of what the public knows about drugs is both scary and wrong.
"It's like taking a chemical helicopter ride above my life," says psychotherapist Charles Wininger. "Then I can come back down and rededicate myself to the way I want to be living."
A 71-year-old therapist comes out of the "chemical closet" to promote MDMA as a means of self-discovery
Rick Doblin, a leading force in America's psychedelic renaissance, imagines a world of "mass mental health" facilitated by formerly demonized drugs.
New documentary features Sting, Sarah Silverman, Anthony Bourdain, Carrie Fisher, and others discussing the good, bad, and ugly of LSD.
The Multidisciplinary Association for Psychedelic Studies (MAPS) is making MDMA and other drugs medically legitimate and socially acceptable.
Despite notable progress in policies regarding pot and psychedelics, the war on drugs always finds new targets.
The host of Hamilton's Pharmacopeia is already exploring what a post-prohibition world is going to look like.
The host of Hamilton's Pharmacopeia is exploring what a post-prohibition world will look like.
Sarah Rose Siskind's monthly show Drug Test is creating a world of educated psychonauts one trip at a time.
Tao Lin's Trip details how the author's experience with LSD, DMT, psilocybin, and more blew his mind while making him more human.
One year after their final sessions, three-quarters of the subjects no longer qualified for a diagnosis.
MDMA, which was banned by the Drug Enforcement Administration in 1985, could be available by prescription as soon as 2021.
Banned Since 1985, MDMA could soon be approved as a PTSD treatment.
Veterans turn to forbidden cures for relief from their nightmares.
The designation should speed the drug's approval as a prescription medicine, which could happen as soon as 2021.
Serious researchers are about to do what Timothy Leary never managed: Get government approval for LSD, MDMA, and more.
A half century after the psychedelic movement came to a screeching halt, MDMA scientists are making the most of a second chance.
Successful clinical trials would lead to MDMA's removal from schedule I.
And other fun notes from the world's largest gathering of psychedelic researchers.
Banned in 1985, the "empathogen" could be legally available as a psychotherapeutic catalyst as soon as 2021.
Surveys combined with hair tests indicate that MDMA adulteration is common.
Impossibly potent marijuana edibles, formaldehyde in e-cigarettes, pills of war, MDMA disguised as Halloween candy, and superhuman flakka zombies.
Super-potent pot, formaldehyde in e-cigarettes, the supersoldier pill, MDMA in trick-or-treat bags, and "$5 insanity"
There's no evidence anyone has ever passed off marijuana edibles or Molly tablets as Halloween candy.
How the government makes drugs more dangerous
Fear of meth, bath salts, salvia, MDMA, and heroin correspond loosely, at best, to actual trends in drug use.