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Clinical trials

Person holding hydroxychloroquine tablets |  © Amlan Mathur | Dreamstime.com

COVID-19

Do Hydroxychloroquine and Ivermectin Work?

Five years after Donald Trump declared a national COVID-19 emergency, here's what the research says.

Ronald Bailey | 3.11.2025 2:45 PM

An illustration of a pancreas |  © Ssrpstudio | Dreamstime.com

Innovation

Pancreatic Cancer Vaccine Shows Potential in Early Trial

The five-year survival rate of people diagnosed with pancreatic cancer is currently 13 percent.

Ronald Bailey | 2.28.2025 2:25 PM

Robert F. Kennedy Jr. | Chen Mengtong/China News Service/VCG/Newscom

Vaccines

Just Asking Questions About RFK Jr.'s Senate Hearing

And not much liking the answers.

Ronald Bailey | 1.30.2025 1:15 PM

A hand holding MDMA capsules | MAPS

MDMA

FDA Declines To Approve MDMA-Assisted Psychotherapy as a PTSD Treatment

The FDA, which approved the protocols for the studies it now questions, is asking for an additional Phase 3 clinical trial, which would take years and millions of dollars.

Jacob Sullum | 8.12.2024 1:10 PM

VaccinatedDreamstime

Clinical trials

It's OK To Let People Take Risks for Medical Science

A recent study finds that human challenge trials are largely safe.

Ronald Bailey | 5.2.2023 5:35 PM

Eliminating taxation on compensation for being a human guinea pig is just good public policy. | Illustration: Lex Villena;  Bewuel

Medicine

I Gave Myself Severe Diarrhea for Science. Don't Tax Me for It.

Eliminating taxation on compensation for being a human guinea pig is just good public policy.

Jake Eberts | 4.5.2023 6:00 AM

PaxlovidBoxDreamstime | Valerio Rosati | Dreamstime.com

Coronavirus

The FDA Should Immediately Approve Pfizer's Anti-COVID-19 Pill Paxlovid

The omicron COVID-19 variant is likely to sweep through the country in the next month or so.

Ronald Bailey | 12.14.2021 1:15 PM

HumanChallengeVirus | Александр Марко | Dreamstime.com

Vaccines

U.K. Approves Clinical Trial That Will Deliberately Expose Volunteers to the COVID-19 Virus

It's a good idea, but it should have been done much earlier.

Ronald Bailey | 2.18.2021 3:45 PM

MasksNewscom | Salvatore Laporta/ZUMAPRESS/Newscom

Coronavirus

Masks Not Very Effective at Protecting Wearers, Says New Danish Study

But masks are still likely to prevent infected people from transmitting the virus.

Ronald Bailey | 11.18.2020 4:25 PM

TrumpMask | SplashNews/Newscom

Coronavirus

Hydroxychloroquine Is Conspicuously Absent from Trump's COVID-19 Treatment Regimen

And that's good.

Ronald Bailey | 10.5.2020 3:35 PM

VaccineCovidKaraevgenDreamstime | Karaevgen | Dreamstime.com

Coronavirus

COVID-19 Coronavirus Vaccine Race Rushes Toward the Finish Line

Safe and effective vaccines by the end of this year?

Ronald Bailey | 7.27.2020 6:00 PM

hydroxybottledreamstime | Simone Hogan | Dreamstime.com

Coronavirus

Hydroxychloroquine 'Is Not a Treatment for COVID-19. It Doesn't Work.'

The antimalarial drug is being removed from United Kingdom's RECOVERY trial evaluating COVID-19 therapies.

Ronald Bailey | 6.5.2020 2:30 PM

hydroxyLancetDreamstime | Theaphotography | Dreamstime.com

Coronavirus

The Lancet's Hydroxychloroquine Study Is Retracted by Its Authors

The observational dataset on which it was based could not be properly audited.

Ronald Bailey | 6.4.2020 5:00 PM

HydroxyHandDreamstime | Amlan Mathur | Dreamstime.com

Coronavirus

Does That Malaria Medicine Work on COVID-19 After All?

A major study in The Lancet said it doesn't—but it may have relied on fabricated data.

Ronald Bailey | 6.3.2020 1:10 PM

HydroxyPackageVirusDreamstime | Amlan Mathur | Dreamstime.com

Coronavirus

Hydroxychloroquine and Chloroquine Increase COVID-19 Patients' Risk of Death, Says New Study

The World Health Organization pauses clinical trials in light of disturbing new results.

Ronald Bailey | 5.26.2020 3:20 PM

CoronavirusVaccineDreamstime | Feverpitched/Dreamstime

Coronavirus

Human Challenge Trials for Coronavirus Vaccines Are Ethical and Should Be Initiated Quickly

Volunteers would earn cash for the risks they take on our behalf.

Ronald Bailey | 5.7.2020 4:15 PM

remdesivirNewscom | Ulrich Perrey/dpa/picture-alliance/Newscom

Coronavirus

FDA To Announce Emergency Use Authorization for Antiviral Remdesivir as COVID-19 Treatment

Promising randomized controlled trial results indicate the drug shortens time to recovery

Ronald Bailey | 4.29.2020 4:15 PM

RemdesivirChinaDreamstime | Stig Alenäs | Dreamstime.com

Coronavirus

Leaked Study Finds No Benefit from Antiviral Remdesivir in Treating COVID-19

A contrast with last week's leaked results from a University of Chicago study

Ronald Bailey | 4.23.2020 4:20 PM

GileadRemdesivir | Gilead

Coronavirus

Antiviral Is Reportedly Effective in Treating Severe Cases of COVID-19

STAT reports leaked comments of University of Chicago researcher

Ronald Bailey | 4.16.2020 5:35 PM

HydroxychloroquineDreamstime | Amlan Mathur | Dreamstime.com

Coronavirus

Hydroxychloroquine Trial for Treating COVID-19 Disappoints

"The best available evidence does not support the use of hydroxychloroquine in COVID-19."

Ronald Bailey | 4.16.2020 3:10 PM

CoronavirusVaccineMilospaulineDreamstime | Milospauline/Dreamstime

Coronavirus

Deliberately Infect Healthy Young People To Test Coronavirus Vaccines, Propose Bioethicists

An idea that could really speed up vaccine development

Ronald Bailey | 3.27.2020 5:30 PM

Hydroxychloroquine |  Gary Hider | Dreamstime.com

Coronavirus

Trump Suggests Anti-Malarial Drug Chloroquine Is an Effective Treatment Against COVID-19

FDA is reportedly cutting red tape to give expanded access to COVID-19 patients.

Ronald Bailey | 3.19.2020 3:15 PM

Large image on homepages | portokalis/iStock

Drugs

FDA May Soon Allow MDMA Prescriptions for PTSD

MDMA, which was banned by the Drug Enforcement Administration in 1985, could be available by prescription as soon as 2021.

Jacob Sullum | 7.31.2018 6:00 AM

Large image on homepages

Donald Trump

Trump and How to Speed Up FDA Regulatory Approvals

Slashing the restraints on the agency's slow and burdensome process.

Ronald Bailey | 3.1.2017 3:15 PM

Large image on homepages

Culture

Broken Science

What happens when cancer doctors, psychologists, and drug developers can't rely on each other's research?

Ronald Bailey | 1.19.2016 6:00 AM

Large image on homepages

Civil Liberties

Should Terminal Patients Be Allowed to Try Experimental Drugs?

"Right to try" laws offer hope for people trying to save their own lives.

Alex Manning | 12.23.2015 12:00 AM

Pharmaceuticals

Cost to Develop New Pharmaceutical Is Now $2.6 Billion - Up from $800 Million, Says Study

Ronald Bailey | 11.18.2014 2:35 PM

Politics

Building a 21st Century FDA

A better way to fast track new pills for old ills

Ronald Bailey | 4.24.2012 4:45 PM

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