Prohibition Killed Matthew Perry
Three people have pled guilty and two will go to trial over the actor's death.

Last month, federal prosecutors indicted five people for the overdose death of a celebrity the previous year. Three have pleaded guilty so far, and this month, a trial date was set for the other two. Many of the details certainly reveal heinous behavior, but the case makes clear that prohibition itself bears the most responsibility.
On October 28, 2023, Matthew Perry—the actor best known as Chandler Bing on the long-running sitcom Friends—died at his Los Angeles home. The county medical examiner announced in December that Perry's death primarily resulted from "the acute effects of ketamine"; the full autopsy indicated that he drowned in his hot tub when a sizable dose of the drug depressed his breathing and caused him to slip into unconsciousness.
Ketamine was developed for use in anesthesia and pain relief before gaining a reputation as a club drug in the 1980s. Recent evidence suggests it can be used to treat persistent depression and addiction. In the right context, it's also quite safe: A 2022 scientific review of 312 overdoses and 138 deaths in which ketamine was present found "no cases of overdose or death related to the use of ketamine as an antidepressant in a therapeutic setting."
Perry struggled with drug and alcohol addictions for most of his adult life, but the summer before his death, he said he had been sober for 18 months. As investigators would discover, Perry was staying clean through therapeutic ketamine treatments but eventually became addicted to the treatment itself; when doctors refused to increase his dosage, he sought the drug elsewhere.
Among those indicted are physicians Salvador Plasencia and Mark Chavez, as well as Kenneth Iwamasa, Perry's personal assistant. Iwamasa admitted in a plea agreement that "beginning in or around September 2023," Perry asked for help "procuring illegal drugs for [his] personal use." Iwamasa worked with Plasencia, who supplied ketamine from his own practice, as well as purchasing some from Chavez, who operated a ketamine clinic. Both men falsified prescriptions and medical records to justify ordering ketamine that could be sold to Perry on the side.
At times, Plasencia came to Perry's house to administer the drug himself, but he also showed Iwamasa how to administer it "through an intramuscular injection" and left behind syringes for future use. At the same time, Iwamasa worked with Erik Fleming, a drug dealer who is also charged, to get even more ketamine for Perry to take.
The indictments include truly odious details of people taking advantage of Perry's desperation for profit. "I wonder how much this moron will pay," Plasencia allegedly texted Chavez. "Lets find out."
By the final week of Perry's life, he was receiving multiple injections per day. According to his plea, Iwamasa had found Perry "unconscious at his residence on at least two occasions" in October. On the day Perry died, despite having received two injections already, he told Iwamasa to prepare the hot tub and "shoot me up with a big one." Iwamasa later returned from running errands to find Perry dead.
Iwamasa and Chavez have pleaded guilty, as has Fleming. This month, a March 2025 trial date was set for Plasencia and Jasveen Sangha, Fleming's supplier who is colorfully referred to in the indictments as "the Ketamine Queen." Each defendant potentially faces a decade or more in prison.
Perry's death, again, is tragic—all the more so due to the circumstances behind it, as people took advantage of his desperation for their own gain. But many of the charges are hard to square with reality.
For one thing, Perry did not overdose, and his drugs were not tainted; while the medical examiner listed ketamine as the primary contributing factor in his death, the most direct cause was drowning. "Matthew Perry drowned while intoxicated on ketamine the same way people routinely drown while intoxicated on alcohol," Ryan Marino, a doctor of toxicology and addiction medicine at University Hospitals in Cleveland, told Filter.
Andrew Stolbach, a physician and toxicologist at Johns Hopkins Hospital, "said it's unlikely Perry would have died if he was not in a body of water," VICE reported last year. "It's really dangerous to use sedative drugs in a pool, especially alone, or a bathtub," Stolbach added.
There is also no use of force alleged in any of the indictments. After all, Iwamasa did not inject Perry with ketamine against his boss' will—rather, he was following Perry's direction every step of the way. At times, the indictments even depict desperation: On October 7, Iwamasa texted Plasencia about buying ketamine the next morning, before texting later that day, "I just ran out," and indicating he needed it sooner.
Earlier this month, Deanna Kizis wrote in Vanity Fair that Iwamasa may not have felt he had a choice, as "the assistant community knows all about how hard it is to say no to a Hollywood boss."
None of the doctors or drug dealers are alleged to have used force, either: Perry came to them willingly, seeking drugs to nurse his addictions. And there is no allegation that any of them intentionally inflicted harm on him—after all, why would any drug dealer seek to harm a reliable client? If anything, the indictments show a commitment to keeping Perry around: Plasencia texted Chavez to make sure he had access to a consistent supply of ketamine, saying they "would be best served not having him look elsewhere" and should "[b]e his go to."
It's also worth noting that California has no law by which state prosecutors can charge a street dealer for selling drugs that someone dies after taking, so long as the drugs weren't intentionally tainted without the user's knowledge. But federal law is another story: If dealers sell a "controlled substance," and "if death or serious bodily injury results from the use of such substance," then federal prosecutors can bring charges punishable by "not less than 20 years or more than life" in federal prison.
It's not clear that increasing penalties for people who supply people with the means of their ultimate undoing has the intended effect: In the Philippines, where the punishment for drug trafficking is death, traffickers merely trick or coerce others into muling the drugs on their behalf. British grandmother Lindsay Sandiford has spent a decade on death row after she was caught smuggling cocaine into Indonesia.
This is not the first time in recent years that federal prosecutors have thrown the book at drug dealers after a celebrity's death. In 2018, rapper Mac Miller died of a drug overdose. In the years since, two dealers have received prison sentences of more than a decade each.
And actor Michael K. Williams died of an overdose in September 2021 after using heroin that had been laced with fentanyl. Last year, the dealer who sold him the drugs was sentenced to 10 years in prison.
Instead of throwing the book at the people who sold Perry ketamine, federal prosecutors and legislators should take a good look at the system that pushed him toward more unscrupulous sources for what he was seeking.
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Mathew Perry killed Matthew Perry.
A little personal responsibility is required.
Please watch your language.
The words "responsibility" and "accountability" are not tolerated by any leftist and the punishment for employing such vulgar language can be severe.
You've been warned.
He really should have known that ketamine in a hot tub by yourself is a really bad idea.
Just like he should have known that getting completely hammered every night and showing up to work still drunk from the night before was a bad idea. He was an addict, and his judgment was impaired by his addiction.
Perry shouldn't have chosen to be an addict.
What we need is common sense hot tub control. On the other hand it's not hot tubs that kill people. It's unconscious people in hot tubs that kill people. In any case this dude was already past his due date.
So outlaw unconsciousness, what could possibly go wrong.
That’s why in CA we consider water hazmat.
A required MSDS on all bathtubs could’ve prevented this tragedy.
"A little personal responsibility is required"
^THIS +1000000000
[tilts hand]
Injecting someone else with a big dose of ketamine, setting up the hot tub for them, and then leaving them alone... I'm not entirely convinced you aren't 0.00% culpable for anything that results.
But, yeah, "prohibition" is way down the list, right around "hypocrisy".
Instead of throwing the book at the people who sold Perry ketamine
This isn't a job for prosecutor discretion.
This is a legislative problem.
We should ban hot tubs. They are death traps for people with preexisting heart conditions who just happen to want to use some drugs at the same time. If it saves one opiate addict - it might be worth it.
Yeah you can have my hot tub when you pry it from my dangerously overheated dead fingers.
The clinic near campus drugged me with sth for passing a kidney pebble back in 86. The local LP treasurer, a cop, kindly fetched the prescribed stuff for me. Instead of stopping peristalsis and deadening the pain, it still hurt but seemed farther away, with less duress. I thought it was CPZ plus a kicker, but now suspect maybe ketamine. Life these days is more like being in Clint 'n Burt's "City Heat", with everyone drinking furniture polish remover because of prohibitionism.
So Perry was like the old woman who swallowed the fly, replacing one set of addictions with another with little sense of self control or preservation. The people who enabling him did not want him to die, but like the OceanGate people running the Titan submersible were too greedy and stupid to realize they were puuting their client in a circumstance that would kill him.
I am not where in the article a reasoned case that prohibition killed Perry is ever made.
The article actually makes it quite clear that it's NOT Prohibition that killed him. He didn't take a tainted dose. He was able to get enough of the substance to medicate as much as he wanted, keeping him from double dipping and taking multiple different substances. He got as much of the drug he wanted, and died as a result of free use of the drug outside of the medical system.
This is actually just the proof that full legalization won't create utopia. Some people will still become addicted to substances and will suffer or die as a result. The libertarian argument is just that prohibition didn't save Matthew Perry, who would have died regardless, and it does more harm than good overall.
The libertarian argument is just that prohibition didn’t save Matthew Perry, who would have died regardless, and it does more harm than good overall.
It should similarly/also be noted that at least Iwamasa should've/would've/could've still been facing prosecution and Plasencia should/would/could still face revoking of his license even without Prohibition.
It really does sound like Iwamasa killed him, even if under Perry's instruction, and Plasencia violated any oaths about "Do No Harm" by showing Iwamasa how to inject Perry and not, apparently, advising him not to give a "big" dose right before going into the hot tub or whatever.
For both there's a case about foresight but, as indicated, a case would/could/should be made.
I'm not going to let Iwamasa off the hook, but I'm also going to propose this alternative scenario.
Iwamasa refuses to dose Perry before he gets into the hot tub. Perry throws a fit, throws him out of his house, doses himself, and gets into into the hot tub. He still dies.
Alternatively, Iwamasa refuses, takes the drugs with him. Iwamasa is then fired. Two weeks later, Perry's new assistant that he hired complies with Perry's request to shoot him up and prepare the hot tub, and Perry still dies.
The fact is that Perry really wanted to get a large dose of a sedative and jump into a hot tub. Iwamasa still shouldn't have done it, if for nothing other than the self-interest of not wanting to be involved in putting his boss in a risk-of-death scenario. But refusing to do what he did still might not have saved Perry.
No… NO. Had Perry been able to get Ketamine from an FDA-approved-so-we-know-what's-in-it vending machine on the corner of Hollywood and Vine, NONE of this would have happened!
Except he did through the licensed professionals that were cooking their books to supply him so it was as good as you get. Unless the argument is to let everyone who violated other laws outside drug laws off the hook I don't see how any of this is prohibition.
I'm sympathetic to the argument that prohibition causes damage. 82% sympathetic!
Let's try a different narrative.
"C-list Hollywood actor with back problems got addicted to Oxycontin. Because of prohibition, it was getting more difficult for him to legally acquire Oxycontin so, after months of increasing pain, beloved sit-com star purchases what he believed were Oxycontin pills from a drug dealer under a 405 overpass. Crushes them up and snorts them off a mirror through a $5 bill. Dies from overdose because it turns out the pills were laced with fentanyl".
That's a 'prohibition kills people' story. This ain't that story.
Reason killed Matthew Perry. Their "all drugs, all the time" drumbeat clearly had its intended impact. Congratulations.
Yeah, without the scourge that is Reason, drug abuse would have ended decades ago.
This article is very poorly reasoned, however, because Matthew Perry absolutely would have killed himself with his addiction in libertopia. There's nearly nothing you could argue that would frame prohibitive drug policies as the cause of death since he got as much drugs as he wanted, administered without any red tape in the way.
A smart writer, addressing this topic, would acknowledge this fact, and point out that there's no panacea to drug addiction. They would argue that prohibition and restrictive drug policies failed to save Matthew Perry, and do harm to a lot of people. Other people, who lack Perry's resources, would have been economically destroyed or had to switch to other more addictive substances to feed their habits, or would have been more at buying something that was contaminated.
Legalization isn't going to just create utopia, it's still going to have bad outcomes for many people. It's just the best overall policy because it's built on personal responsibility, reducing the size and scope of the nanny-state, and will ensure better outcomes on the whole.
“My body, my choice” takes it on the chin yet again.
As investigators would discover, Perry was staying clean through therapeutic ketamine treatments but eventually became addicted to the treatment itself; when doctors refused to increase his dosage, he sought the drug elsewhere.
Hang on, now. You're blaming this on prohibition, but you're also admitting that, in a purely therapeutic setting, he became addicted to the drug to a degree that went beyond therapeutic. It makes it difficult to blame this 100% on prohibition because even if there was no war on drugs, a responsible doctor would still refuse to increase a prescription if they believed someone was become substance-dependent, which would still create a feedback wherein the drug-seeker is looking for less ethical people to feed his habit.
It's not like Perry died because he couldn't get enough of the substance he wanted and therefore got it from sketchy places where it was mixed with something else. This also isn't a case of being denied painkillers and then self-medicating with heroine or opium.
For one thing, Perry did not overdose, and his drugs were not tainted; while the medical examiner listed ketamine as the primary contributing factor in his death, the most direct cause was drowning.
This is very clearly the outcome we'd have seen in a world where ketamine is NOT a controlled substance. He was able to get as much as he wanted, though he had to pay through the nose for it to procure it illegally. But abolish the FDA and the war on drugs, and he still ends up just buying as much ketamine as he wants directly from a sketchy medical professional who is willing to instruct his assistance on how to administer the dose. This is basically the libertarian outcome since he was wealthy enough to bypass all the restrictions in place that are meant to prevent drug-seeking behavior.
One of Perry's main substance abuse demons was alcohol, which he could buy as much of as he wanted and could consume completely legally. If he'd remained addicted to that, there's still a very good chance of him dying in a hot tub eventually.
It sounds like this was a man who had a particular susceptibility to addictive behavior. In breaking his addiction, he addicted himself to something else. His addictions killed him, not Prohibition or the War on Drugs.
Three people have pled guilty
You belie your lede with your sub-title. I didn't even read the article. I didn't even need to get to it to see that your headline was fake news.
Matthew Perry killed Matthew Perry. Three people helped, and admitted as much. Prohibition had nothing to do with it.
A ketamine clinic. A clinic for Ketamine.
Is this article really suggesting that had Ketamine been available in any dose and quantity over the counter at a convenience store- fully-regulated-by-the-FDA-so-we'd-know-what's-in-it that he'd be alive, well, and at the top of his game? Or wait, was the ketamine he was getting packaged, labeled and approved by the FDA? Since it... you know, comes from a clinic and even comes in nasal spray form?
When I was a kid, Ketamine was for horses, wasn't FDA regulated, and was as ineffective as ivermectin.
Of course, you shoot up a horse with twice the amount of Ketamine as the label indicates and it dies (or loses a race as the case may be), people stop buying your product because it kills their horses (or makes them lose)... all while still being illegal for human use.
But borders and gender and species and chemistry are just abstract social constructs, or something.
I can have some sympathy for the AA but administering drugs then abandoning Perry was an easily foreseeable tragedy. Anything he went out to get he could have had delivered. The people that forged their records to supply him violated protective rules but sure, they wouldn't be here if K was available at the corner store by the kilo. How is the drug dealer coming out the innocent caught in the crossfire.
Damn Repub... *reads article more carefully* Democrats and their prohibionismists.
Bob Ferguson will be an even bigger disaster for Washington State than Jay Inslee. Ferguson is the piece of shit who ran Arlene’s Flowers out of business for not catering gay weddings.
Reason continues to miss the larger picture here, despite it having been pointed out to them repeatedly. Only addicts are killed by prohibition – except for a very few innocent bystanders killed by cops in drug war raids and by gangster turf shoot-outs. Although the effects of prohibition and the war on drugs extend far beyond deaths, Reason is unlikely to win over any hearts and minds towards ending prohibition and the war on drugs by trying to claim the high ground on protecting the lives of drug addicts and alcoholics. One friend who is normally very empathetic and sympathetic told me, “Let them overdose and die and be done with it.” Aside, of course, from the obvious "killing addicts to protect them," I mean.
Only addicts are killed by prohibition
Infrequent users are just as likely to get killed by overdosing on what they did last time with something more potent.
“Let them overdose and die and be done with it.”
Families call that "tough love".
Your family calls it ‘tough hate’.
“killing addicts to protect them” ... from themselves.
Well Said... The very premise is a distortion of ?helping?.
The only separating factor of Government is Gun-Force (death threats).
It's all my body my choice until it comes to drugs.
"As investigators would discover, Perry was staying clean through therapeutic ketamine treatments"
Define "clean" for me then.
Ketamine cleaned him out, with extreme prejudice.
Addiction is sad. The best solution to addiction is to avoid it. You know that smoking is addictive, so don't ever light up a cigarette. You know that heroin is addictive, so don't every snort/swallow/inject heroin.
I know it sounds simplistic, and it is, but it works.
Perry killed himself don’t make him a victim dude had so many chances.
Could he be any more deceased?
The DEA puts pressure on doctors and hospital not to prescribe certain drugs, such as Norco, despite the fact that similar to Ketamine, patients using Norco under a doctor's supervision do not die of overdoses. The DEA, however, needs deaths from overdoses and thus it threatens doctors and hospitals until the cease to treat the patients. The patients then have to seek the drug on the street where it adulterated and often it is just a lethal dose of Fentanyl. The more Fentanayl deaths the larger the DEA budget.
Also DEA rules are absurd. They classify a drug addict someone who takes 1/2 Norco in the morning and sometimes an other 1/4 of 1/2 in the afternoon as a drug addict if he takes Norco for more than two weeks. In reality, people can take low dose Norco for decades with no risk provided they can get their supply thru a regular doctor -- and not thru the illicit market.