How Drug Warriors Made the 'Opioid Epidemic' Deadlier

Restricting access to pain medication drove nonmedical users toward black-market substitutes.


According to the lawsuits that four drug companies agreed to settle last week, the "opioid epidemic" was caused by overprescription of pain medication, which suggests that curtailing the supply of analgesics such as hydrocodone and oxycodone is the key to reducing opioid-related deaths. But that assumption has proven disastrously wrong, revealing how prohibition makes drug use deadlier.

Per capita opioid prescriptions in the United States, which began rising in 2006, fell steadily after 2012, reflecting the impact of government efforts to restrict and discourage medical use of these drugs. Yet in 2019, when the dispensing rate was lower than it had been since 2005, the U.S. saw more opioid-related deaths than ever before.

Last year, according to preliminary estimates from the Centers for Disease Control and Prevention (CDC), that record was broken once again: Opioid-related deaths jumped by 40 percent. As opioid prescriptions fell, the upward trend in fatalities (which typically involve more than one drug) not only continued but accelerated.

That perverse effect was entirely predictable. The crackdown on pain pills drove nonmedical users toward black-market substitutes, replacing legally manufactured, reliably dosed products with drugs of unknown provenance and composition.

While that was happening, illicit fentanyl became increasingly common as a heroin booster or replacement, making potency even more variable and unpredictable. In 2020, according to the CDC's projections, "synthetic opioids other than methadone," the category that includes fentanyl and its analogs, were involved in 83 percent of opioid-related deaths, up from 14 percent in 2010.

Nowadays fentanyl is showing up in black-market pills sold as hydrocodone or oxycodone and even in stimulants such as cocaine and methamphetamine. Its proliferation is a response to the very supply control measures that were supposed to reduce drug-related deaths.

To the extent that the government succeeds in exerting pressure on the supply of illegal intoxicants, it encourages traffickers to distribute more-potent drugs, which are easier to conceal and smuggle. Since fentanyl is far more potent than heroin, a package weighing less than an ounce can replace one that weighs a couple of pounds.

Synthesizing opioids is also a less vulnerable and much cheaper process than production that relies on poppy crops. RAND Corporation researchers estimate that heroin is at least 100 times as expensive to produce as fentanyl, adjusting for potency.

Black-market drugs were already iffy because of prohibition; the prohibition-driven rise of fentanyl has made them even more of a crapshoot. And these are the substitutes that nonmedical opioid users resorted to after drug warriors succeeded in reducing the supply of pain pills.

That policy also has hurt bona fide patients by depriving them of the medication they need to make their lives bearable. Last week the American Medical Association (AMA) again urged the CDC to revise its opioid prescribing advice, which has been widely interpreted as imposing hard caps on daily doses.

"Patients with pain continue to suffer from the undertreatment of pain and the stigma of having pain," wrote AMA Board of Trustees Chair Bobby Mukkamala. "This is a direct result of the arbitrary thresholds on dose and quantity contained in the 2016 CDC Guideline."

Although "physicians have reduced opioid prescribing by more than 44 percent since 2012," Mukkamala noted, "the drug overdose epidemic has gotten worse." The government mistakenly assumed that the availability of particular intoxicants was causing drug-related deaths, which is clearly not true in light of the social, economic, and psychological factors that plausibly explain last year's surge, such as financial insecurity, emotional stress, isolation, and disengagement from meaningful activities.

The COVID-19 pandemic magnified those problems, but it did not create them. A 2019 Joint Economic Committee report on "deaths of despair" noted that "drug-related deaths have been rising since the late 1950s."

The increase in opioid fatalities is the latest manifestation of that long-term trend. By now it should be clear that when it comes to drug-related "deaths of despair," the root problem is the despair, not the drugs.

© Copyright 2021 by Creators Syndicate Inc.

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  2. It also drove medical users to street drugs as well. If you were taking opioids for legit chronic pain and were suddenly cut off, seeking to replace that relief with street drugs doesn’t automatically make you a non-medical user, especially before the switch.

    There’s also an increase in pain related suicides; medical users who were cut off or just never given relief from intractable pain outright killing themselves.

    But hey, look how big the settlements are!

  3. Are the pain meds addictive? Yup. Have they been abused? Yup. Does that mean they should have been pulled from the legal market? Nope.

    1. Except that pain meds utilized for serious actual chronic pain is less addictive than for those who don’t need the pain meds.

  4. Awe; The war on drugs — proving more-so everyday to be nothing but a “crony socialist” attempt at monopolizing the peoples healthcare industry.

    Remember that Constitutional Amendment that gave congress the authority to dictate everyone’s healthcare?

    Ya; Me neither.

  5. Sadly we have a medical profession that just throws drugs at people in order to cure them (actually just to treat symptoms). There was a time when they assured us these opioids were not addictive, but it was untrue and now shitty places like China manufacture enough to kill everyone of us, while undermining our southern border selling to cartels.

    1. You can’t be a “licensed” medical professional without first *learning* to throw over-priced drugs at people in the USA.

      And there’s no such thing as a “medical professional” without the monopolized “licensing” of the State for which the tax-payers will fund your unearned *bill*.

      IEEE, ISO, etc, etc, have the right idea. Keep the Gov-Gun-Forces out of “quality management standards” otherwise you end up with Commie-Indoctrination/Education camps.

    2. You have a choice to follow, or even solicit, a doctor’s advice. Prohibition, on the other hand, forcefully terminates your choices. Attacking healthcare choices in response to critics of prohibition, is a nihilistic attack on human agency itself.

      1. Obamacare — “Attacking healthcare choices”.

  6. Fentanyl is the Drug Wars greatest success. It enables an endless “We told you so” response.
    And if creating a Drug-Free America means killing every last American then that’s what’s going to happen. They’ll do it for the children

  7. As a former primary care physician, I subspecialized in part because patients on opioids were so nasty about even the thought of tapering them. Most of them try to call in the prescription early and they openly admit to taking them inappropriately. Hell, one patient popped some in front of me and started CHEWING them.

    There are numerous studies that find opioids to be ineffective for long term chronic pain in part because it allows the user and physician to ignore the actual reason for the pain. In fact, stopping opioids and treating the problem leads to a better quality of life according to a well crafted study. The reason people died in higher numbers last year was because they were bored at home and decided to use these drugs more recreationally.

    Sullum of course offers no solution, but seems to imply we go back to the old ways of prescribing opioids for everything. Maybe he can sit in with me and watch patients threaten to “go to the street” if I take 5 pills away this month. It’s like someone threatening to shoot themselves if I take away some of their recreational activity for the month.

    1. And what are your patients supposed to do while you are trying to find out what the cause of their pain is to treat it?

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