Anonymous gunmen attacked the Rayesa checkpoint outside Arish in Sinai on Friday morning, the 34th such attack in the last 19 months.
Security forces exchanged fire with the assailants, who fled. There were no injuries.
Eyewitnesses said that gunmen targeted the checkpoint from the south of the international road and the high mountain areas surrounding it.
The troops combed the surrounding areas, in addition to inspecting the passing cars and questioning their occupants.
Rayesa checkpoint has been attacked 34 times since the beginning of the 25 January revolution, most recently on 31 August.