World Anti-Doping Agency Nightmare In The Making

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Researchers at Johns Hopkins University have developed a compound that inhibits the muscle limiting protein myostatin in mice. Injecting the compound twice a week built rodents with some muscles 60 percent bigger than their untreated confreres. The researchers hope that if the compound proves to be safe that it will one day help patients suffering from muscle wasting diseases like muscular dystrophy. However, you can be sure that the athletic enhancement underground will be following this research closely. In the ongoing physical enhancement arms race, researchers are also developing a test that can detect the level of circulating myostatin in humans.

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  1. that’s a pretty big fucking mouse.

    just imagine how the O RLY owl will have to bulk up to compete!

    🙂

  2. We are still many years away from seeing how this kid is going to turn out.

  3. Oh man. This will make those “World’s Strongest Man” contests on The Ocho even better.

    No longer will they drag just one fire truck. Oh no, they’re gonna be pulling an entire parade’s worth of civic equipment.

  4. OPRATIC VOICE: HERE I COME TO SAVE THE DAY….

  5. Actually, if it is proven safe, it will not be banned (see creatine or multivitamins, whey protien, etc). The anti-doping agencies seek to ban unsafe supplements, such as EPO, so that athletes won’t be forced to compromise thier safety in order to compete.

  6. The anti-doping agencies seek to ban unsafe supplements

    HA! Utter crap. Ephedra is extremely safe.

  7. YEAH MOUSE BIG BUT HOW MUCH CAN HE BENCH!? HOW MUCH CAN HE BENCH!?

  8. MP – the clinic research I’ve perused seems to indicate that ephedra is certainly not safe, especially for athletes. It appears to raise core body temperature, increase heart rate, and increase blood pressure. Simply put, it doesn’t seem very safe to me. I don’t think it should be illegal, but I have no problem with a sport’s rule commission banning it’s use…

  9. It appears to raise core body temperature, increase heart rate, and increase blood pressure.

    Better ban coffee too. BTW, safe doesn’t mean “has zero potentially harmful effects on the body”.

  10. Excess volumes of caffeine are already banned. Btw, I am an edurance athlete, and I do use creatine and caffeine for performance enhancement, as well as gatorade, GU, whey protien, carbo-loading, etc. There is a significant safety difference between drinking 2-3 cups of tea before a marathon and drinking 20-30 cups of tea…

  11. There is a significant safety difference between drinking 2-3 cups of tea before a marathon and drinking 20-30 cups of tea…

    It is grossly inaccurate to equate a 25mg dose of ephedra (the typical OTC dose in one serving) to 20-30 cups of tea. If that’s not what you were implying, then what were you implying?

  12. I’ve been doing tons of reading for the past year when ever a new development has occurred with the Myostatin gene. I am surprised by how quickly it has come to, not just development, but to human testing! So far, I have seen no traces of any negative reactions or developments in any of the mice or in the humans who have naturally low occurring myostatin genes.

    How “natural” will the end-product be? Will it be something you can buy over the counter? (I doubt that Wyeth would ever allow that!). How easy will it be for the black market pharmacies to re-create the end-product?

    Just some questions still yet to be answererd.

  13. Of course, the researchers could have achieved the same muscle-building results just by putting a piece of carpet in the mouse’s cage.

  14. There is a significant safety difference between drinking 2-3 cups of tea before a marathon and drinking 20-30 cups of tea

    Especially to the guy running behind you, who may slip at some point…

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