Dopesick
The new Hulu miniseries promotes pernicious misconceptions about opioids, addiction, and pain treatment.

In the third episode of the Hulu miniseries Dopesick, Randy Ramseyer, an assistant U.S. attorney in Virginia who is investigating Purdue Pharma's marketing of OxyContin, undergoes prostate cancer surgery. Although he tells a nurse his postoperative pain is off the charts, he refuses to take the OxyContin she offers, saying he wants nothing but Tylenol.
Ramseyer later describes that incident as a narrow escape from the clutches of pharmacological slavery. "I very easily could've become addicted to Oxy," he says. "And it wouldn't have been the disease that killed me; it would've been my medication. I got lucky."
The implication is that opioids are not an appropriate treatment even for severe postsurgical pain. Ramseyer's decision and his justification for it illustrate how Dopesick, ostensibly about the misdeeds of one unscrupulous pharmaceutical company, promotes pernicious misconceptions about opioids, addiction, and pain treatment.
A 2021 review of the evidence in the journal Frontiers in Pain Research concluded that "the prevalence of opioid use disorder associated with prescription opioids is likely < 3%." Dopesick, which is based on a 2018 book of the same name by journalist Beth Macy, presents that uncommon outcome as if it were typical. We never see a single patient whose life was, on balance, improved by prescription opioids. The resulting impression is that patients who take opioids for pain generally regret it.
Because OxyContin is not qualitatively different from other opioid analgesics, Dopesick's indictment of it amounts to an indictment of the whole drug category, which the show portrays as unacceptably dangerous in nearly every context, with the possible exception of dying cancer patients. Dopesick's creators seem to think everyone else, no matter how life-impairing his pain, should follow former Attorney General Jeff Sessions' cruel prescription: "take some aspirin" and "tough it out."
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I have not knowingly taken any opioids. My wife has after several back operations. A few doses and then consciously stopping with no issues. We don't live in this TV drama life.
"I have not knowingly taken any opioids. "
If you find yourself taking them to deal with pain that is chronic, and upping your dose to relieve pain that doesn't stop, opioids aren't the answer. Treatment for the underlying causes is the wiser (though more expensive) course to take.
Reefer Madness with better production values
This came out like 6 months ago, is that how long it will be before we hear about the Durham report here on Reason?
The Durham report was submitted in January 1839 by 'Radical Jack' Lambton, AKA Lord Durham. If Reason hasn't covered this by now, chances are they never will.
News flash: anything from Hollywood (or any media production company) is bullshit. Especially when they claim it is true.
Apparently more than a third of the population has suffered from or is suffering chronic pain, ie pain that is more or less continuous over long periods of time. Treatment with opioids risks addiction.
Life isn’t safe. It ends in death 100% of the time.
" It ends in death 100% of the time."
All the opiates in the world aren't going to change that.
No, but they can make chronic pain tolerable.
It's not a good long term strategy. Better to address the root of the problem, even if it means major disruption like finding a new line of work, for example. I know the feeling you get from taking opioids, and I can see the allure of them. But their dangers have been well know for thousands of years. Pain is mother nature's way of telling you something is wrong. When you're in agony with you hand over a flame, best thing to do is remove your hand. Keeping you hand in the fire and taking a pill to stop the pain is not the best.
Seriously? One third. I think you pulled that stat outta yer ass.
Show your work.
"Show your work."
I've worked on jobs with my feet and my hands
But all the work I did was for the other man
And now we demands a chance
To do things for ourselves
we tired of beating our heads against the wall
And working for someone else
https://www.youtube.com/watch?v=4hj1iWqoYEc
(S)-(+)-Nirvanol
Polymyxin B is an antibiotic produced by Bacillus polymyxia strains. It is effective against gram-negative infections. https://www.bocsci.com/polymyxin-b-sulfate-cas-1405-20-5-item-58398.html
Thx a lot for this
And for this