The family of late locked-in syndrome sufferer Tony Nicklinson and paralysed road accident victim Paul Lamb have lost their right-to-die challenges.
The Court of Appeal upheld a ruling that Mr Nicklinson had not had the right to ask a doctor to end his life. His widow is planning a further appeal.
Mr Lamb who won a battle to join the Nicklinson case also plans to appeal.
But a third paralysed man won his case seeking clearer prosecution guidance for health workers who help others die.