Psych Drug News Roundup
* The FDA contemplates adding warnings about possible psychoses caused by popular ADHD drugs such as Ritalin, Adderall, and Strattera.
*Los Angeles law firm Baum Hedlund files a class-action suit against GlaxoSmithKline over youth suicides allegedly caused by Paxil.
*Largest-ever study on treating depression with drugs finds that if one doesn't work, another might. Apparently good news for treatability--"the new findings mean that roughly half of people who suffer from depression can get over it, not just improve their symptoms, with adequate medication," says a CBS/AP report. But bad news for our actual understanding of what it all means, since
the drugs used in the study--Celexa, Wellbutrin, Zoloft and Effexor--work in very different ways yet had roughly equal effectiveness when it came to treating depression. This suggests that the underlying brain mechanisms of depression are far more complicated than simple notions of a single chemical imbalance…
In news only tangentially related to psychiatric drugs, last night's "Return of Chef" episode of South Park was peculiar in peculiar ways, not really a gut-buster or full-on well-targeted assault, and appeared to solve the "Chef's Voice" problem by cutting and pasting old Isaac Hayes lines. It did roughly seem to analogize Scientology to a weird club of old-fashioned gentlemen adventurers secretly (or not-so-secretly) dedicated to child sexual abuse, but this seemed more random than a well-thought-out comic conceit.
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The child abuse thing was probably put in there because L. Ron Hubbard was widely believed to have pedophilic tendencies.
It wasn't a full-on assault at scientology, more of a commentary on how the club took their friend with their crazy brain control. The specifics of what the club entails aren't really important, because the result to the boys on the show (and the show's creators) are pretty much the same regardless of what the club was about: they lost their friend, and were sad about it.
That, and obliquely comparing scientologists to child molestors while maintaining plausible deniability about it is pretty damn funny.
I think so, anyway.
It must be weird to be a Reason drug reporter right now.
The FDA is issuing warnings about drugs given to patients, including children, for psychiatric conditions.
Do you condemn this? Applaud it? You need a least a couple of days to figure out how this fits into your belief system.
In the mean time, cluster-blog several items, without comment. It's a good way to buy time.
It must be weird to be a Reason drug reporter right now
Quite weird indeed, joey boy. I mean, like the FDA, yes, the F fuckin' DA is, like, considering issuing warnings! OH MY FUCKING GOD WARNINGS!! Involviing children even! Holy Shit!
This is truly a hard time to be a Reason drug reporter.
It is easy to be a Reason drug reporter.
All you need is a hatred of the drug war and a belief in the "drugs cause addiction" myth. i.e. one foot on the brake one foot on the gas.
Is Addiction Real?
M. Simon
ummm, do you actually read reason's drug war reporting? I think Thomas Szaz is even a contributor for fucks sake.
Celexa, Wellbutrin, Zoloft and Effexor--work in very different ways yet had roughly equal effectiveness when it came to treating depression.
That tells me that they're mostly placebos.
For example:
"http://www.psychiatrictimes.com/p020906.html
Antidepressants Versus Placebos: Meaningful Advantages Are Lacking
by Irving Kirsch, Ph.D., and David Antonuccio, Ph.D.
Antidepressants are widely believed to be exceptionally effective medications. The data, however, tell a different story. Kirsch et al. (2002a) analyzed the data sent to the U.S. Food and Drug Administration by the manufacturers of the six most widely prescribed antidepressants (fluoxetine [Prozac], paroxetine [Paxil], sertraline [Zoloft], venlafaxine [Effexor], nefazodone [Serzone] and citalopram [Celexa]). Their research showed that although the response to antidepressants was substantial, the response to inert placebo was almost as great. The mean difference was about two points on the Hamilton Rating Scale for Depression (HAM-D). Although statistically significant, this difference is not clinically significant (Jacobson et al., 1999)."
The side effects increase the placebo effect.
joe-
Yeah, that's a tough one.
On the one hand, they're criticizing drugs.
But they're criticizing psychiatric drugs, so that's different.
But some people use these drugs for pleasure, not medicinal use, so maybe we shouldn't say nasty things about the drugs.
But these sorts of warnings show the absurdity of drawing lines between types of drugs. So there's a certain ironic benefit here.
Then again, these drugs are mostly sold by big corporations, so saying nasty things is a bad idea.
And it is the government, so that's bad.
So, when you add it all up, you have to conclude that...fuck it, this shit is too complicated. Let's smoke a joint.
I propose that more libertarians should adopt that strategy for solving ideological dilemmas. Instead of getting into a pissing contest with each other, just say "Fuck it, let's smoke a joint." If we can't resolve our differences, we can at least ignore them at 4:20.
Joe, good comment, brother. A lot of my comments here are intended to elicit whether HnRers really want safety & efficacy testing of drugs, albeit from a private source.
As best as I can tell, the answer is "yes" to private testing and warnings so long as there is no legal liability for underdone warnings or faulty testing. Sounds like the pre-FDA regime, which was not a good one. Sounds useless.
Then you have Bailey who on one post recognizes the wonderful work 20th (and 19th) century government did in lengthening lifespans by fighting communicable disease with tax money. Then he writes a post not too long later, admitting that asthma (sp?) is getting worse. Gee, too bad we have moved past the 20th century way of fighting disease. O well, at least maybe we will get some expensive asthma drugs so that we can pay our insurance premiums with our pharma stock dividends.
You want to cut the government -- cut a few weapons programs.
But if you want to cut the FDA and public health -- maybe it is better to have some plan that is better than "let's just turn the clock back to 1905."
"... this seemed more random than a well-thought-out comic conceit."
In other words, a standard South Park episode.
This is a perfect example of why the government sucks. Ritalin has been harshly criticized for decades. But now, since the FDA rode in on it's horse and is contemplating (yes, contemplating) issuing warnings, the American populace is suddenly worried, nay I say, very concerned about the alleged health problems surrounding this drug.
Screw them...and the horse they rode to town on. Where was the FDA thirty years ago? Still patting itself on the back that thaldomide (sp) never crossed the Canadian border I suppose.
For all of you
Do you condemn this? Applaud it? You need a least a couple of days to figure out how this fits into your belief system.
joe, sounds like you may be in need of some of this medication.
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