A patient infected with the novel coronavirus has died in France, according to the health ministry.
The virus, which is similar to those which cause Sars and the common cold, emerged last year.
Out of 44 confirmed cases around the world, 23 people have now died with most infections linked to travel to the Middle East.
The virus causes pneumonia and, sometimes, organ failure. Most patients have had other health problems.
The 65-year-old, who had been travelling in Dubai, died in hospital on Tuesday.
Another patient who shared a hospital room with the man has caught the infection.