BRITAIN'S state-run health service is in need of a fundamental change of culture to restore public trust after patients at one hospital received appalling standards of care, an inquiry has found.

The chairman of the investigation, top lawyer Robert Francis, said the failings at Stafford Hospital in central England had revealed the need for major reforms across the whole of the National Health Service (NHS).

Data suggests there were between 400 and 1200 more deaths than normal at the hospital between 2005 and 2008, but it is impossible to say whether these were caused by the neglect.