The Methuselah Manifesto

Witnessing the launch of Immortality, Inc.?

Los Angeles, California—If you’re under age 30, it is likely that you will be able to live as long as you want. That is, barring accidents and wars, you have centuries of healthy life ahead of you. So the participants in the Longevity Summit convened in Manhattan Beach, California, contend. Over the weekend Maximum Life Foundation president David Kekich gathered a group of scientists, entrepreneurs, and visionaries to meet for three days with the goal of developing a scientific and business strategy to make extreme human life extension a real possibility within a couple of decades. Kekich dubbed the effort the Manhattan Beach Project.

Tech entrepreneur and futurist Ray Kurzweil opened the conference with a virtual presentation on exponential technology trends that are bringing the prospect of achieving longevity escape velocity ever closer. “We are very close to the tipping point in human longevity,” asserted Kurzweil to the conferees. “We are about 15 years away from adding more than one year of longevity per year to remaining life expectancy.” This has been labeled by summiteer and life-extension guru Aubrey de Grey as longevity escape velocity. Achieving escape velocity, according to Kekich, would mean that “your projected day of reckoning moves further away from you rather than closing in on you.”

“Health and medicine will be a million times more powerful in 20 years,” Kurzweil declared. He predicted that the complexity of biology will yield to the exponential powers of applied information technology and take off. He cited Moore’s Law which predicts doubling of microchip functionality and halving their costs every two years. The decrease in cost and increase in speed of sequencing whole human genomes is outpacing even Moore’s Law. In 2000, the first genome was sequenced after 14 years and at a cost of $3 billion. Now various startups offer the potential to sequence an individual’s DNA for less than $100 in under an hour.

The goal of the summit was to devise scientific and business strategies with the goal of demonstrating the capability to reverse aging in an older human being by 2029. By then, Kurzweil argued, people will be beginning their intimate merger with information technologies, biotechnologies, and nanotechnologies. Kurzweil, age 61, emphasized, “Something I am personally interested in is not just designer babies, but designer baby boomers.”

Going Back to Move Forward

Anti-aging research is a rich and varied territory right now. Researchers are finally beginning to get a handle on the actual causes of aging. With this increased scientific understanding, some researchers now believe they are on the way to figuring out how to stop it, and—eventually—how to reverse it.

University of California, Riverside biochemist Stephen Spindler reported on his research seeking caloric restriction mimetics. It is well established that restricting many mammal species to about two-thirds of what they would ordinarily eat extends their healthy lifespans. For example, calorie restricted mice live up to 50 percent longer, and experience less heart disease and cancer than those who eat as much as they want. Spindler is now screening a variety of compounds including pharmaceuticals to see if they mimic the effects of calorie restriction in mice. He presented early results that show that some compounds, like cholesterol lowering statin drugs and the immune suppressant rapamycin, do seem to increase mouse lifespans. However, Spindler added that more is not necessarily better. Mice receiving combinations of compounds are not living any longer. “I personally would caution people taking large amounts of supplements in combination to be careful,” said Spindler. The good news is that several major pharmaceutical companies are working on calorie restriction mimetics known as sirtuins.

Michael Rose, a biologist at the University of California, Irvine, has been breeding long-lived fruit flies to one another for decades. Rose’s work is built on the premise that natural selection is the cause of aging. Specifically, natural selection works to keep organisms healthy and alive until after they have reproduced. Once they’ve reproduced, natural selection no longer works to prevent the accumulation of damage that leads to aging and death. Your body is no longer needed by your germ cells once their genes have moved on to the bodies of your children.

Using artificial selection for longevity, Rose has produced fruit flies that live four times longer than normal, the human equivalent of being healthy at age 300. The Methuselah flies are more fecund and better at handling environmental stresses than are normal flies. Since fruit flies and humans share many similar genes, insights garnered from the genomics of long-lived flies are being used by Genescient LLC to develop anti-aging supplements for people. The company plans to release its first product in 2010. “In my world biological immortality is possible,” said Rose.

William Andrews, head of Sierra Sciences (motto “Cure Aging or Die Trying”) talked about his company’s project to identify compounds that lengthen telomeres. Why do that? Telomeres are repeated sequences of DNA that cap the ends of chromosomes to keep them from unraveling and to keep them from binding to other chromosomes. At conception, telomeres are about 15,000 repeats long. Each time a cell divides it loses about 100 repeats, growing ever shorter. When the repeats get short enough, cells generally receive a signal that tells them to die. Andrews argues that telomeres control aging in cells and thus control aging in us. A new study this month reports that centenarians have longer telomeres than controls do.

According to Andrews, when an adult’s telomeres get down to about 5,000 repeats they die of old age. By looking at telomere length in a blood sample, Andrews claimed, “I can tell how old you are and how long you have before you die of old age.” (For the curious, Spectracell offers a commercial telomere length test.) The only cells in our bodies that do not suffer telomere shortening are reproductive cells because the enzyme telomerase keeps adding new repeats as they divide. The goal of Sierra Sciences is to develop compounds that will reactivate telomerase in somatic cells to stop telomere shortening. After screening more than 160,000 compounds, Sierra has come up with 33 that activate telomerase and lengthen telomeres. “This would be the biggest thing to hit the planet, if we can turn these into drugs,’ said Andrews. Also represented at the summit was TA Sciences which manufactures a telomerase activator as a supplement called TA 65, which is derived from the astragalus plant. Cost? A mere $8,000 for a six month supply.

Why do some people live to be over 100 years old? That’s the question that Stephen Coles, head of the Supercentenarian Research Foundation (SRF) is trying to answer. Supercentenarians are people who are over 110 years old. In the world there are 76 currently validated supercentenarians, 72 are female and 4 are male. The genetic underpinnings of their longer lives are still murky. However, Coles has performed a number of autopsies and he has found that most died of senile cardiac amyloidosis, the accumulation of amyloid fibers in their heart muscles.

John Furber, founder of Legendary Pharmaceuticals, discussed the problem of accumulating crosslinked proteins and sugars inside and outside of cells, e.g., fibers like those that killed Coles' supercentenarians. The digestive organelles inside cells called lysosomes slowly become clogged with advanced glycation end-products (AGEs). The promise of one product that aimed to break up damaging crosslinks, alagebrium, has faded with the financial prospects of the company that developed it. If old fibroblasts, the cells that produce connective fibers, could be rejuvenated, say by restoring their telomere lengths, then, perhaps drug interventions like alagebrium might not be needed. Interestingly, there is some evidence that periodic fasting upregulates autophagy, the process by which cells digest accumulating cellular and extracellular junk.

Anti-aging research is not for the faint-hearted. Biologist Michael West was one of the founders of the biotech stem cell company Geron. He later founded Advanced Cell Technology which worked on therapeutic cloning. Therapeutic cloning, a.k.a somatic cell nuclear transfer, involves inserting nuclei from specific patients into human eggs to produce stem cells that are immunologically matched to those patients. The goal would be to transform these stem cells into other cells—nerve, muscle, immune system cells—which could be used to repair damaged or old tissues and organs.

That’s the theory, but no one has been able to perfect the practice; no stem cell lines have been derived from cloned human embryos so far. West now heads up BioTime, which is increasingly focused on using induced pluripotent stem cells (IPS cells). IPS cells are created by dosing normal adult cells, say skin cells, taken from a patient with various embryonic factors that cause it to revert to an earlier stage of development. IPS cells can be transformed into other types of cells which can be used to repair damage or rejuvenate tissues and organs. For example, new hemangioblasts, the precursor cells of blood, could be used to reconstitute and rejuvenate the human immune system.

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  • Spoonman||

    Single-payer immortality for all!

  • ||

    No, if people in the current administration already think it is wasteful to spend extra to get new technology 2 years before Europe does, then for sure it is wasteful to get this kind of technology.

    Not to mention the Christian Right who think life extension is immoral.

    If Obamacare passes, and we get huge new regulation and taxes, I worry about innovation.

    Even if stuff happens, we'll have to fight against the statists in government who will want to regulate and give this away for free to everyone (it would not be fair for the rich to live longer but not the poor), and that will kill innovation too, without early adopters to fund development, and giving it away for free will drive away investors.

    This is, quite literally, another way socialism will condemn is to death.

  • ||

    condemn us, dammit, broken finger make typing hard. eat, dig, thing

  • ghina||

    I dont' think so plut,.

  • bladder infection||

    Long live science. Though I much prefer to live healthy instead of tube.

  • Lack of Sleep||

    Another secret to longer life, getting better sleep.

    It's said that living day to day with under 8 hours of sleep sheds 7 years off your lifetime.

    120 years, here I come.

  • Macca||

    That's me screwed then. I spend almost all my waking hours running our wedding guitarist business and only get 5 or 6 hours sleep a night!

  • The Grim Reaper||

    Job-killer.

  • ||

    Really interesting topic that cuts to the core for me right now.

    Regards
    John
    myp2p
    myp2p eu

  • masters in health admin||

    Advance your career in the field of healthcare

  • W. A. Mozart||

    There was a time when we thoght the longer the opera, the better the opera.

  • ||

    I like major variety of music. Why choose single one?

  • symptoms of kidney infection||

    I believe the longer the opera is, the likelihood that you will stay awake will be greatly reduced.

  • Mike M.||

    If you think that health care is expensive now, wait until everyone starts living forever!

  • Drinky Bird||

    You don't think this will require ongoing treatments? So of course we must ensure that everyone (e.g., sex offenders, gang bangers, etc.) has equal access to these treatments in order to be fair. I mean if we don't give treatments to death row inmate Scott Peterson (Lacie's killer) then he is the victim of cruel and unusual punisment. On the other hand, if we do give him treatments, he could spend 900 years in jail, which could also be viewed as cruel and unusual.

  • Zeb||

    What the fuck is Lacie?

  • Drinky Bird||

    Your pink panties.

  • ||

    I've read in some science fiction books where withholding treatment is used as punishment. They aren't jailed, just not given the youth technology for 20 years. Then they live the rest of the time with 20 years older bodies than everyone else

  • Anton Sherwood||

    On another hand, in Blish's Cities in Flight slow death by withholding of anti-aging is considered more cruel than the firing squad.

  • ||

    Mike M; Actually, if everyone has the health and vitality of a 25 year old, think how cheap health care will be.

  • ||

    I would like to die of old age with the vitality of a 25 year old!

  • Mike M.||

    This is going to wreak serious havoc on Viagra sales.

  • Internet Marketing||

    haha, don't we all...

  • ||

    This excites me, but... question: what happens to the planet's population even a single generation after we're all ostensibly immortal?

    We're banking on space colonization, right?

    Just making sure I'm on the same page, here.

  • Spoonman||

    I'm always banking on space colonization.

  • ||

    +1

  • ||

    the gun is good! the penis is evil!

  • Reason||

    Actually nothing drastic happens to population. See this study:

    http://www.fightaging.org/arch.....manity.php

    "nalysis of already existing computer programs for population projections revealed that many of them are based on short-sighted assumptions of small incremental changes in human life span, and they do not allow making detailed projections for the oldest age groups of the population (which are often collapsed into one single 85+ year category). For this reason, many already existing computer programs of population projections are not well suited for the purpose of this project. Therefore, with the support of the Methuselah/SENS foundation, a new demographic projection software has been developed in this study, which was then validated for consistency of results with traditional approaches. This new demographic software is based on generally accepted cohort-component method of population projections. A number of different demographic projections is considered in this project, assuming several scenarios of life extension.
    A general conclusion of this study is that population changes are surprisingly slow in their response to a dramatic life extension. For example, we applied the cohort-component method of population projections to 2005 Swedish population for several scenarios of life extension and a fertility schedule observed in 2005. Even for very long 50-year projection horizon, with the most radical life extension scenario (assuming no aging at all after age 50), the total population increases by 35 percent only (from 9.1 to 13.3 million). Moreover, if some members of the society reject to use new anti-aging technologies for some religious or any other reasons (inconvenience, non-compliance, fear of side effects, costs, etc.), then the total population size may even decrease over time. Thus, even in the case of the most radical life extension scenario, population growth could be relatively slow and may not necessarily lead to overpopulation."

  • ||

    This excites me, but... question: what happens to the planet's population even a single generation after we're all ostensibly immortal?

    If only the reasonably well-off gain immortality due to it being expensive, not much, since on average they are breeding at under the 2.1 child replacement rate.

    The long term result would likely be an even lower reproductive rate, as crowding would cause housing and food prices to rise.

    That's why crowded urban areas are population sinks -- the high cost of living causes people to choose to have fewer or no kids.

  • The Man||

    No, space colonization won't work. At a current growth rate of about 2% per year and an average adult weight of 100 pounds we are producing 14 billion pounds a year of people.

    The recent Mars Rover missions transported 2350 pounds to the Martian surface at a cost of $820M. If we assume that is all transport cost then the cost per pound to Mars is $348K. To transport 14 billion pounds of people to Mars (without food, water or air) would cost more than $5,000,000,000,000,000 (that's 5 quadrillion dollars), more than 80 times the GDP of the entire world in 2008.

    So if we devoted all of our new wealth, every year, to shipping people to Mars, we could handle less than 1.5% of the growth. If you want to go somewhere else with an atmosphere, it'll cost more. If you want to build millions of space stations, it'll cost more. Some space exploration fans might suggest that we can export our way out of the population problem, but it's never gonna happen.

    We could, perhaps, enforce some sort of final solution and just fire the excess people into the sun, but it's cheaper and more efficient to eat them. We can go into space for profit or to put some of our eggs in a different basket, but we won't reduce population by exporting it.

  • ||

    That's assuming that space exploration will always be as expensive as it is today, which is really very silly considering the speeches Ray Kurzweil has been giving about exponential growth. We probably need some new technology to enable significant space colonization, such as a space elevator and a large base on the moon, but that will happen in time. And don't forget commercial space-flight is starting to pick up as well. I'm not saying it'll be a viable option as the moment longevity starts to increase, but neither will overpopulation be a problem right away. Remember, if we placed solar panels in just 5% of the Sahara desert, we would be able to power all our existing technology. The sun has plenty of energy to go around, we just have to start using it.

  • The Man||

    Obviously, being quantitative is as useless as being skeptical when BIG ideas are in the air. When Ray Kurzweil is selling $43/pound tickets to Mars, he can call me and maybe I'll go. (The $43 comes from reducing the cost of a trip to Mars by a factor of 8000 so transporting our excess consumes only about 1% of global GDP.) Until then we're all safe from being transported for littering.

  • Kroneborge||

    Maybe you would have to choose sterility to get immortality treatments.

    Also, I doubt this stuff will be cheap. By design if for no other reason. So we won't have that many people living that long.

  • Drinky Bird||

    Eternal life is a right.

  • ||

    They'll probably just run it like health care. Eternal life is a fundamental right, so we're gonna tax the hell out of the middle class so they can't afford it and then give it to the parasites among us (thus creating a truly permenant constituency for gubmint largesse). Ultimately, it will be like one big Galtian strike, if only because the lions share of those worthy of life (eternal or not), will have passed on, leaving only the dregs of society and the well-connected elite. Let's see Emmerlich make this doomsday scenario a theatrical hit.

  • WWJGD||

    It is shameful that we are the only industrialized nation that does not have universal immortality!

  • The Man||

    You won't even notice the cost. According to the BBC, "The average life expectancy for a male child born in the UK between 1276 and 1300 was 31.3 years. In 1998, it is 76." Costs decline and markets adjust our expectations. We expect to live into our 70s now at a cost we can afford. I see no reason that won't continue to be the case.

  • WWJGD||

    Someone please explain what the fuck is a futurist?

  • Xeones||

    A futurist is someone who futures for a living, WWJGD. Duh.

  • Tony||

    In the future getting hit by a bus is gonna suck a whole lot more.

  • Speaking of Trials||

    Babble incoherently much?

  • ||

    You must be new here.

  • Michael||

    This whole immortality thing strikes me as being kinda stupid. Since living forever makes saving for retirement an infinite endeavor, what sort of marketable skills can one possibly expect to have at 167? You'd have 92-year-olds running circles around you.

  • ||

    I wouldnt worry too much about that. Our congressional overlords are smart, they'd probably raise the SS eligibility age to 75 in a world of immortality and show us a five year budget window that would prove the system is still solvent.

  • Kroneborge||

    Maybe though we woudn't have retirement, just start working a bit less.

    For example, once you get the house paid for, and have some cash in the bank, switch to a 4-6 hour day maybe 4 days a week.

    Enough to keep the mind occupied, but leave plenty of time for play.

  • ||

    yeah because I'm sure technology won't make your body actually feel younger, just limp along getting more and more feeble, that's the real goal, right

  • Anton Sherwood||

    Imagine going back to school, every thirty or sixty years, to study an entirely different field!

  • Grandma||

    People seek eternal life, yet they don't know what to do on a rainy Sunday afternoon.

  • Whippersnapper||

    Yeah, immortality is BOOORING!!

  • shimano sahara||

    I agreed, after doing the same thing for ages!

  • ||

    Genius.

  • Drinky Bird||

    I masturbate.

  • ||

    You're a jerk, Dent. A complete kneebiter.

    (Read "Life, the Universe, and Everything" for the reference.)

    Also, I'm scheduled to turn 31 in a month, so as Glenn Reynolds likes to say, faster, please.

  • Vermont Gun Owner||

    Aw, you beat me to it... by a couple of years.

  • ||

    Our society is headed towards:

    The gun is good! The penis is evil!

    Don't worry, the liberals will start distributing guns when resources to maintain the eternals becomes scarce.

  • Mike Laursen||

    Manhattan Beach is a pretty good place to find designer baby boomers.

  • skr||

    I thought Bruce Sterling had some interesting notions in "Holy Fire". Basically, since the old people had all the money a gerontocracy was established. The trick about getting the life extension procedures was that you had to live a squeaky clean lifestyle, because no of the corporations that were developing the procedures wanted to risk all that money on development and the potential for investor pullout on someone who does drugs, smokes, and doesn't exercise.

  • ||

    Term limits would be a must, no more counting on Strom Thurman kicking the bucket.

  • The Man||

    I don't get it. You libertarians scream like little girls when somebody says that government purchase of football stadiums is a good idea and then somebody says this:

    "One major barrier to cracking the problem of aging is a shortage of researchers. Computer scientist Peter Voss, the founder of Adaptive Artificial Intelligence, aims to solve that researcher shortage by creating the equivalent of thousands of researchers and research assistants by means of artificial general intelligence. "

    And you guys are discussing its implementation details and environmental impact. A couple of weeks ago it was singularists saying that we will soon be able to upload our minds into computers and thereby achieve immortality. Where's the critical thinking? Where's the evidence for artificial PhDs? You guys would have a better understanding of where science is and how it's done if you watched Futurama, seriously.

    Am I the only one that remembers Steve Martin's bit "You can be a millionaire and never pays taxes. . .first get a million dollars."

  • ||

    I thought this thread WAS a brainstorming session for a Futurama script.

  • Edwin||

    The Man,
    what the hell are you even saying in your comment? Stop rambling

  • The Man||

    OK. The short form: I am surprised to see that libertarians are such credulous boobs.

  • ||

    Please report to the nearest processing facility for exsanguination and repackaging.

  • Anton Sherwood||

    You expect to have all the underlying research set out in an article like this?

  • monk||

    Christians are going to be pissed.

    What would they be Pro-life and anti-life?

  • ||

    Next step is applying this to law... only the Aryans can marry... "undesireables" off to the camps...

    Eugenics wearing any disguise scares the carp outta me...

  • Edwin||

    why is anybody even taking this article seriously in the comments? I didn't even bother to read it.

    Everybody dies. Period. And regardless of what any nerdo can write in reason magazine, they'll probably continue to die around 70 - they might push the average up to 80 or 90, but that's it.

    I thought libertarians were supposed to be the ultimate realists. Who's believing this stuff?

  • Kroneborge||

    Wait, why does everyone have to die, especially in the 70-80 range. That's like saying everyone has to get around by walking or riding a horse.

    We have cracked the genome, now it's just a matter of time before they figure out how to turn off ageing.

  • Edwin||

    just being a realist. I'm not saying life spans aren't going to increase - just not dramatically anytime soon, which from what I understand, this article is implying.

    Not to mention it's just possible that 60+ is just a natural biological limit. From what I understand, most old people die from specific health complications, like cancer or heart disease. But even if we find universal cures for these, when you're talking about people over 60, you're just going to get more complications. All systems eventually fail.

    Just remember that NOT everything is possible. It's NICE to believe magical things - we all LIKE to believe them - but doesn't mnake them true. Start thinking like that and next thiong you know you'll be telling people you've invented a free energy machine.

    Not to mention you're not going to convince anyone of anything with wild-eyed, amazing claims of what the future can be like.... Well, it'll get more readers for articles and magazines, but that's about it.

    It's nice to sit around and talk big, but it's all just a giant circle-jerk.

    The guys who spend years doing grueling work just to make the widget-bracket welding machine 10% more efficient at the ACME corp. are far more important to the world - however uninteresting and little their impact may be.

  • Kroneborge||

    Oh, I agree that there is a natural limit around 80-100 or so. But that limit is based on biological processes that are subject to change.

    If you can get your body to start acting like it did when you are younger, and keep rejunvinating itself you can get past that.

  • Edwin||

    we (humanity - including the researchers mentioned in the article) doesn't know NEARLY enough about the human body and metabolism to make that claim - don't jump the gun

  • ||

    yeah that damn optimism of scientists! they are jumping the gun hoping their research might lead to something fruitful within the next 50 years! they should be saying "this wont' work maybe in a few centuries"

    You realize the difference between gene therapy and clean water and good health care? No one is saying what WILL happen, just what might happen. gene therapy is a revolution just like attacking germs was.

    But the pessimists and naysayers have never, ever, changed society for the better.

  • Edwin||

    No, this isn't about being reasonably hopeful about the advancement of science - you're deliberately misconstruing my words

    this is about people making wild claims. There ARE a lot of people here who ARE saying that huge leaps in life expectancy WILL happen soon.

    Jumping the gun and making wild claims is damaging. It confuses people about the nature of science and what to expect - and it scares idiots as to the implications of technology well before anything serious has ever happened a la Philip K. Dick movies. We don't need more fodder for statists to pass more laws for what MIGHT happen with techonology.

    It's crazies who make wild claims about science who never change society for the better. Idiots who spend all their time talking big and doing very little.

    It's just like socialists who talk big but who know nothing about anything specific and who never do anything. College professors who've never produced ANYTHING but claim they know how to change the world into utopia. Dumbass college kids who'll say the government should provide safe housing for everyone, yet who don't know how even a single house is built.

    We need more people thinking smaller and more specific, and actually producing something, and understanding that progress is made in little steps.

    You're calling me a naysayer just because I'm not screaming from the rooftops about immortality and free energy machines and grand unified theories of physics.

    It may be fun to talk huge, but it does nobody any good. Time to grow up.

  • ||

    You seem to know about socialism as much as you do about capitalism: Nil. Otherwise you would not just repeat empty phrases you picked up on TV or elsewhere on the media - that's the repetetive level of kindergarten. Not even your last sentence is correct, because you talk huge and yet you know nothing about what you talk about. Time to remember you are old but forgot to grow up.

  • Anton Sherwood||

    If you're the same Edwin who bragged about not reading the article, then it's not surprising that you don't know what research is being done.

  • ||

    200 years ago you were the guy saying everyone dies at 50 at the latest, why even talk about living longer.

    hey wait, if you were saying that 200 years ago, what is your secret?

  • ||

    The question that can't help crossing my mind is WHY people want to live forever...who is so afraid of death that they want to stave it off for an unforeseen amount of time? Let's take religious reasons for fear of death out of consideration, as those are controversial.
    We are left with the understandably human fear of the unknown and loss of loved ones, which is what death precisely is. But even if death is simply the collapse of cells and the unique human being passes away into nothing, what is so bad about that if it occurs after a long, well-lived life? Obviously a life cut short is a bad thing, but if someone has lived very well in only 50 years of existence, then surely it wouldn't be that bad to die. Perhaps my perspective will change when I near death myself, but at this moment, if I have accomplished most if not all of my major goals in life, then I don't think I'll have any objections to dying at my current life expectancy of 78. Life is about how you live it, not how long you live it.

  • The Man||

    I'll be blunt: You're an idiot.

  • Kutta||

    I don't think you can argue that death is good without making a fool out of yourself.

  • Kutta||

    I mean Garrett

  • Anton Sherwood||

    Well, what if you live your 78 years without accomplishing your goals? What if you don't figure out what your goals are until old age?

    What if your goal inherently takes two hundred years?

  • Justin||

    If it's predicted that in 15 years we'll achieve "escape velocity", anyone know how the author comes up with 30 as the cut-off age? Wouldn't the cut-off age be closer to 65?

  • Ratko||

    Here all this time I've been thinking a life savored celebrated experienced lived, not feared, or clung on to like a wet rat clinging to a piece of flotsam in flash flood, even if it meant life would be much shortened it would be the way. People who disagreed told me I'd never live to see 17, 17 came, I'd never see 20, 20 came..I was in my late 40s before they stopped that crap, a few because their deaths shut 'em up.

    This life extension science, especially radical extension concepts, it's been around for awhile now, first time I heard of may have been Omni magazine, there's some obvious flaws here and there. Still, those involved seem to find zeal in it, and they're enjoying themselves that's great. It would be heartless to crash a Star Trek convention, don't get me wrong, this has some legitimate science involved. Enthusiasm good, too much, and clarity is lost. I know, my enthusiasm was so great that the possibility that people just couldn't know and I may grow old never was given consideration.

    Well, here I am, 1,500 years? I'm your guinea pig!

    Then again, there seems to be a focus on me-ness, what about other people? Should they be forced watch their youth vanish while forced to suffer in a world packed full of 900 year old geezers who just won't do it and kick the damn bucket or another 600 years?

    Just a thought.

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  • ||

    I was quite happy to see from the article that the conference was in fact larger than I'd expected, when reading about it beforehand. It is great to see not only growth but also this positive sort of coverage :-)
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  • ||

    Some things in here I have not thought about before.Thanks for making such a cool post which is really very well written.

    Regards
    Michael
    My tuttorial:ronitv

  • Exercises for men||

    This was a pretty complex read. I liked the section with the heading Immortality Inc, it took a while to understand but I found it very interesting.

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  • Acid reflux diet||

    Didn't know there's sucha summit. Who wouldn't want to live long.

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  • abercrombie milano||

    My only point is that if you take the Bible straight, as I'm sure many of Reasons readers do, you will see a lot of the Old Testament stuff as absolutely insane.

  • Hilarry||

    “Health and medicine will be a million times more powerful in 20 years,” Kurzweil said, I totally agreed on what he said because it will be happen 20 years from now.

  • granite colors||

    I guess they finally found the case where that argument works on northern liberals.

  • Barbie Patterns||

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